There have been instances MoneyWorks 6 on Windows where MoneyWorks appears to open and run, but when people try to do something they get a message along the lines of: “Please insert the disk <<some removeable disk>>”. We do not know why this happens, but believe it is something to do with backing-up using the Save A Backup as command directly onto a removable device.
The only way we know how to clear it is to zap the registry preferences for MoneyWorks — in RegEdit go to HKEY_CURRENT_USER>Software>Cognito>MoneyWorks {Cashbook/Express/Gold} and click on Preferences and Delete it (Edit>Delete)
You should backup to your hard drive and then move the data file to a thumb drive/usb drive if you need to move it. Then copy to the hard drive of the new computer and open from there.